💊 Pharmaceutical
WFI heating, clean steam generation, bioreactor temperature control and autoclave steam supply.
Pharmaceutical — DSI Applications
Clean and hygienic steam injection for WFI heating, bioreactor control and process solutions
Water for Injection (WFI) & Purified Water Heating
Pharmaceutical manufacturing requires WFI and purified water at controlled temperatures for equipment cleaning, formulation and final rinse operations. DSI heaters constructed in pharmaceutical-grade 316L stainless steel with electropolished internals and FDA-compliant elastomers provide the required hygienic standard. The system heats stored WFI from ambient to 80–85°C for hot storage loops (which prevent microbial growth) or to process temperature as required. The absence of dead legs, low internal volume and self-draining design comply with cGMP requirements.
Batch Reactor & Vessel Temperature Control
Pharmaceutical batch reactors require precise temperature ramp-up from ambient to reaction temperature — often 60–90°C — within a defined time window. DSI systems provide rapid, controllable heat input to the batch using PLC-controlled modulating valves. Unlike jacket steam heating, DSI can be applied inline in the recirculation loop, giving faster response and tighter temperature uniformity across large vessels. The system is validated for repeatability, an important requirement for batch record compliance in regulated manufacturing.
Syrup & Liquid Formulation Heating
Liquid oral formulations — syrups, suspensions, solutions — are prepared at elevated temperatures to improve solubility and reduce viscosity for pumping and filling. DSI heaters deliver the required heat directly to the formulation during recirculation without exposing active pharmaceutical ingredients (APIs) to localised hot surfaces, which can cause degradation. The short residence time at peak temperature minimises thermal exposure.