💊 Pharmaceutical
Vacuum drying of APIs, freeze drying preparation, solvent removal and sterile filling lines.
Pharmaceutical — Ejector Applications
Vacuum drying of APIs, solvent removal and sterile manufacturing vacuum systems
Vacuum Tray & Rotary Dryer Systems
Active pharmaceutical ingredients (APIs) and intermediates are dried under vacuum to remove residual solvents from wet cake or granules, meeting ICH Q3C limits for residual solvents. Steam ejectors maintain vacuum in the dryer at 5–50 Torr absolute, which lowers the boiling point of the solvent to allow drying at low temperatures (typically 40–60°C) without degrading thermally sensitive API molecules. A 2–3 stage ejector system handles the solvent vapour load combined with air in-leakage through the dryer shell and door seals.
Freeze Dryer (Lyophiliser) Vacuum Systems
Freeze drying (lyophilisation) of injectables and biologics operates at very deep vacuum — typically 0.5–2.0 Torr — during the primary drying phase to sublimate ice directly. Steam ejector systems (4-stage) are used to evacuate the freeze dryer chamber initially and maintain working vacuum throughout the drying cycle. The ejector handles water vapour from sublimation combined with air and refrigerant in-leakage, tolerating the highly humid gas stream that would ice up mechanical pumps.